Not sure about the looking pale and tired when still full of energy, although the upset stomach can be a common side effect with Lamotrigine.
The effects on development may be down to several factors. ie:
* Lack of concentration (which is also a side effect of Lamotrigine and can make it harder to hold information in or process it as quickly so it may cause a delay in response time)
* The time lost during seizures (which although may be a few seconds at a time, when added up can work out to be a lot of time over the course of a year, as you mention Anais used to have 100 or more a day, that's vital information that she was losing each time, and now that her seizures are ess frequent, you may see an increase in her development as she is more alert and aware of her surroundings and what is happening)
* Other factors associated with the specific Epilepsy Syndrome such as the part of brain where the seizures originate from. (I myself have problems in my left temporal lobe which affects word recognition and retrieval. Such as when I'm speaking I often get words muddled up with similar sounding words but that have a completely different meaning, and the same when I am listening to what is said to me. Strangely enough it is only an auditory problem as reading, writing, and typing are all fine.
Hope this helps some
Best Wishes
Tania x